Formulasi Sediaan Pomade dan Uji Efektivitas Ekstrak Daun Salam (Syzygium Polyanthum) terhadap Pertumbuhan Rambut Kelinci New Zealand White
DOI:
https://doi.org/10.55606/jikki.v5i3.8332Keywords:
Bay Leaf, Hair Growth, New Zealand White, Pomade, RabbitAbstract
Bay leaves are known to contain flavonoids, tannins, saponins, and essential oils, which have been empirically proven to promote healthy hair. This study aimed to determine the potential of bay leaf extract (Syzygium polyanthum) as an active ingredient in pomade and its effectiveness on hair growth in New Zealand White rabbits. The research method used was an experimental laboratory with four variations of pomade formulations: F0 (without extract), F1 (20%), F2 (25%), and F3 (30%). Evaluations were conducted on physical quality parameters such as organoleptic properties, pH, homogeneity, spreadability, viscosity, and adhesion. Effectiveness testing was conducted on the rabbits' backs for 28 days, measuring hair growth. The results of the study showed that pomade preparations with bay leaf extract had physical qualities that met the requirements for hair growth with various extract effectiveness on the 28th day of peak testing showing Formula I (20%) 0.4 cm, formula II (25%) 0.4 cm, Formula III (30%) 1.0 cm, providing the highest hair growth results, namely Formula III compared to other formulas. The results of SPSS statistical analysis with a significance value <0.05 resulted in differences between treatments. So it can be concluded that bay leaf extract can be formulated into an effective pomade preparation in stimulating hair growth.
References
Adriani, A., et al. (2024). Karakterisasi fisik formula pomade dari ekstrak etanol daun teh hijau (Camellia sinensis L). Jurnal Sains dan Kesehatan Darussalam, 4(1), 38–44. https://doi.org/10.56690/jskd.v4i1.128
Amalia, L. D., Raharjo, D., & Septiarini, A. D. (2023). Formulasi dan uji mutu fisik sediaan spray gel ekstrak etanol daun nipah (Nypah fructicans Wurmb) sebagai terapi pengobatan luka sayat terhadap kelinci (New Zealand White). Journal of Educational Innovation and Public Health, 1(4), 213–234. https://doi.org/10.55606/innovation.v1i4.1884
Amananti, W., & Riyanta, A. B. (2020). Formulation and physical properties of candlenut oil gel pomade (Aleurites moluccana Willd). Jurnal Farmasi Sains dan Praktis, 6(2), 84–89. https://doi.org/10.31603/pharmacy.v6i2.3162
Anggraini, A. (2020). Manfaat antioksidan daun salam terhadap kadar glukosa darah dan penurunan apoptosis neuron di hippocampus otak tikus yang mengalami diabetes. Jurnal Medika Hutama, 2(1), 349–355. http://jurnalmedikahutama.com
Aristyawan, A. D., Yuliarni, F. F., & Suryandari, M. (2024). Skrining fitokimia ekstrak etanol jamur kuping hitam (Auricularia nigricans) dengan metode soxhletasi. [Nama Jurnal], 3(2), 114–123.
Delpia, R., Rizkuloh, L. R., & Adlina, S. (2023). Formulasi dan uji aktivitas antibakteri sediaan facial wash gel ekstrak etanol daun jawer kotok (Coleus atropurpureus (L.) Benth) terhadap bakteri Propionibacterium acnes. Jurnal Ilmu Farmasi dan Kesehatan, 1(3), 260–274. https://doi.org/10.59841/an-najat.v1i2.34
Departemen Kesehatan Republik Indonesia. (2020). Farmakope Indonesia (Edisi IV). Depkes RI.
Diah, et al. (2017). Uji aktivitas antioksidan ekstrak daun salam (Syzygium polyanthum) dengan menggunakan DPPH. Jurnal Akademika Kimia, 3(3), 143–149.
Erwan, M. O., & Parbuntari, H. (2023). Identifikasi senyawa metabolit sekunder pada daun salam (Syzygium polyanthum). Periodic, 12(3), 39. https://doi.org/10.24036/periodic.v12i3.118432
Fakhruzy, et al. (2020). Review: Optimalisasi metode maserasi untuk ekstraksi tanin rendemen tinggi. Menara Ilmu, 14(2), 38–41.
Haryanto, F. K., et al. (2023). Review jurnal: Pemanfaatan daun salam (Syzygium polyanthum (Wight) Walp.) sebagai pengobatan tradisional di Indonesia. PharmaCine: Journal of Pharmacy, Medical and Health Science, 4(1), 20–33. https://doi.org/10.35706/pc.v4i1.8714
Indrawati, T. (2023). Kosmetologi & anatomi fisiologi rambut. ISTN Press.
Lubena, L., et al. (2022). Teknologi pengemasan produk simplisia dan minuman herbal bagi pelaku UMKM di lingkungan Pondok Pesantren Riyadhul Huda di Desa Babakan Ciangsana Gunung Putri Bogor. Dedikasi: Jurnal Pengabdian kepada Masyarakat, 3(1), 77–85. https://doi.org/10.31479/dedikasi.v3i1.215
Mardiyanti, D., & Timur, W. W. (2024). Formulasi dan uji aktivitas fisik sampo antiketombe ekstrak daun salam (Syzygium polyanthum) terhadap pertumbuhan jamur Candida albicans secara in vitro. INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal), 8(1), 165. https://doi.org/10.21927/inpharnmed.v8i1.4290
Maslahah, N. (2024). Standar simplisia tanaman obat sebagai bahan sediaan herbal. [Nama Jurnal], 2(2), 1–4.
Mustaqima, R. S. (2020). Potensi daun salam (Syzygium polyanthum) sebagai insektisida alami terhadap nyamuk Aedes aegypti [Karya tulis ilmiah, STIKES Karsa Husada Garut].
Nurhapiani, & Tanjung, S. A. (2024). Journal of Pharmaceutical and Medicine, 1.
Panca, P., Chandra, B., & Lisnawati, N. (2024). Standarisasi simplisia daun salam (Syzygium polyanthum (Wight) Walp.) berdasarkan parameter spesifik dan nonspesifik. [Nama Jurnal], 6(3), 206–215. https://doi.org/10.54771/8ft48z62
Pradiningsih, A., & Rismawati, R. (2018). Uji efektivitas hairtonic ekstrak biji alpukat (Persea americana Mill.) terhadap pertumbuhan rambut kelinci jantan. Farmasi dan Sains, 2(1), 62–73.
Pratama, A. P. (2022). Gambaran organoleptik, homogenitas, viskositas dan daya lekat pomade rambut dengan berbagai konsentrasi minyak kemiri (Aleurites moluccanus) dan paraffin solidum. [Laporan penelitian]. http://repository.lp4mstikeskhg.org/96/1/ASYILLA%20SHP.docx.pdf
Rasyadi, Y., Fendri, S. T. J., & Wahyudi, F. T. (2020). Formulation, physical evaluation, and stability of pomade containing bitter melon (Momordica charantia L.) leaf ethanol extract. Pharmaceutical Journal of Indonesia, 17(2), 281–291. https://doi.org/10.30595/pharmacy.v17i2.6988
Syafitri, A., Marbun, V. E., & Laia, S. (2024). Formulasi sediaan pomade ekstrak daun meniran (Phyllanthus niruri L.) sebagai perangsang penumbuh rambut pada kelinci. Jurnal Penelitian Farmasi & Herbal, 6(2), 23–32. https://doi.org/10.36656/jpfh.v6i2.1688
Trisnawati, E., Astuti, W., & Kartika, R. (2020). Kemampuan ekstrak metanol daun salam (Syzygium polyanthum) dalam menghambat pertumbuhan Staphylococcus aureus dan Salmonella typhi. Jurnal Atomik, 2020(1), 53–56.
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