Korelasi Trombosit dan Hematokrit Sebagai Indikator Klinis Awal pada Pasien Demam Berdarah Dengue di Rumah Sakit Metro Cikarang Utara
DOI:
https://doi.org/10.55606/jikki.v6i1.9526Keywords:
Dengue Hemorrhagic Fever, Hematocrit, Hemoconcentration, Plasma Leakage, ThrombocytopeniaAbstract
Dengue Hemorrhagic Fever (DHF) is an infectious disease caused by a virus, characterized by decreased platelet levels and increased hematocrit levels due to plasma leakage. The assessment of these two parameters is crucial in evaluating the clinical status and severity of the disease. This study aims to analyze the relationship between platelet count and hematocrit levels in patients with Dengue Hemorrhagic Fever (DHF) treated at Metro Cikarang Utara Hospital. An analytical quantitative approach with a cross-sectional design was used, involving data from 124 DHF patients. The analysis revealed that all patients experienced thrombocytopenia, with an average platelet count of 91,430/μL, while hematocrit levels varied, with an average of 42.56%. Spearman correlation test was employed, showing a significant negative correlation between platelet count and hematocrit levels (r = -0.268; p = 0.003). These findings indicate that the lower the platelet count, the higher the potential for increased hematocrit levels. This supports the correlation between thrombocytopenia and hemoconcentration due to plasma leakage, which is a hallmark of the critical phase of DHF. The results emphasize the importance of regular monitoring of these parameters for early detection of clinical deterioration and determination of appropriate clinical interventions.
References
Aflah Kamila, N. (2022). Hubungan jumlah trombosit dengan kadar hematokrit pada pasien demam berdarah dengue (DBD) usia 6–11 tahun di RSUD Cut Meutia Aceh Utara tahun 2019. Jurnal Kedokteran Syiah Kuala, 22(2), 1412–1026.
Agustin, I., Tarwotjo, U., & Rahadian, R. (2017). Perilaku bertelur dan siklus hidup Aedes aegypti pada berbagai media air. [Nama jurnal tidak tersedia]. (Tambahkan nama jurnal bila ada)
Andromeda, A., Palembang, N. N. F., & Ewangga, B. (2024). Korelasi persentase hematokrit dan jumlah trombosit dengan tingkat keparahan pasien dewasa demam berdarah dengue di RSUD Cibabat Kota Cimahi tahun 2022. Jurnal Integrasi Kesehatan & Sains, 6(1), 36–40.
Comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever. (2015). World Health Organization Regional Office for South-East Asia.
Furrukh, M., Ayaz, S. Bin, Ayaz, F., Rahman, F., Ambreen, S., & Rahman, F. U. (2023). Do hematocrit levels differentiate between complicated and uncomplicated dengue fever? Pakistan Armed Forces Medical Journal, 73(4), 1100–1103.
Hukom, A. O. E., Warouw, S. M., Memah, M., et al. (n.d.). Hubungan nilai hematokrit dan nilai jumlah trombosit pada pasien demam berdarah dengue. [Nama jurnal/tahun tidak tersedia]
Maulin, K. N., & Irma, F. A. (2023). Hubungan jumlah trombosit dan hematokrit dengan derajat keparahan demam berdarah dengue di RSUD Dr. Pirngadi Kota Medan tahun 2019–2021. [Nama jurnal tidak tersedia]
Rianti, E., Metasari, D., Surahman, F. S., Ilmu Kesehatan F., & Dehasen, U. (2022). Hubungan trombosit dan hematokrit dengan kejadian DBD di Rumah Sakit Tiara Sella Kota Bengkulu tahun 2022. [Homepage on the Internet]. Available from: https://journal.bengkuluinstitute.com/index.php/juvokes
Rodrigo, C., Sigera, C., Fernando, D., & Rajapakse, S. (2021). Plasma leakage in dengue: A systematic review of prospective observational studies. BMC Infectious Diseases, 21(1). https://doi.org/10.1186/s12879-020-05786-w (DOI umum referensi — harap cek artikel spesifik)
Tampubolon, C. H., Manalu, E., & Dewi, T. P. (2025). Relationship between increased hematocrit levels and lowest platelet counts with outcomes of dengue fever patients in children. International Journal of Global Health Research, 7(3). https://doi.org/10.37287/ijghr.v7i3.6189
Tarmizi, S. N. (2024). Demam berdarah masih mengintai. Kementerian Kesehatan RI. https://link.kemkes.go.id/mediakom
Umimi, K., Hadi, W. S., & Novalina, D. (n.d.). Hubungan jumlah trombosit dengan nilai hematokrit pada pasien penderita demam berdarah dengue di RS X. [Detail publikasi tidak tersedia]
VBSRN Indraja Sannidhiraju, Sathvika Pilladi, Harika Karri, et al. (2025). Assessing the relationship between hematocrit and platelet count in dengue fever: A prospective observational study. World Journal of Biology Pharmacy and Health Sciences, 21(3), 032–039. https://journalwjbphs.com/node/428
Vikhe, V. B., Khandol, D., Faruqi, A. A., & Reddy, A. (2024). A study on the clinical profile of patients presenting with dengue fever and the precision prediction of dengue severity using platelet count at presentation. Cureus. (Tambahkan volume dan halaman bila tersedia)
Wardhy, A. H., Yaswir, R., & Murni, A. W. (2017). Hubungan jumlah trombosit dengan nilai hematokrit pada penderita demam berdarah dengue dengan manifestasi perdarahan spontan di RSUP Dr. M. Djamil Padang. [Homepage on the Internet]. http://jurnal.fk.unand.ac.id
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
